Evaluation of Fetal Central Nervous
System Anomalies by Ultrasound and Its
Anatomical Correlation
Published: June 1, 2014 | DOI: https://doi.org/10.7860/JCDR/2014/.4437
Deepali Onkar, Prashant Onkar, Kajal Mitra
PARTICULARS OF CONTRIBUTORS:
1. Associate Professor, Department of Anatomy, NKP Salve Institute of Medical Sciences and Research Centre, Nagpur, India.
2. Associate Professor, Department of Radiodiagnosis, NKP Salve Institute of Medical Sciences and Research Centre, Nagpur, India.
3. Professor, Department of Radiodiagnosis, NKP Salve Institute of Medical Sciences and Research Centre, Nagpur, India.
Correspondence
Dr. Deepali Onkar,
175 Bajaj Nagar, Nagpur-440010, India.
Phone: +91-712-2248590, +91-9822248570 E-mail: drdeepalionkar@yahoo.com
Introduction: Central nervous system anomalies are often severe and are the most common indications for therapeutic abortions. Ultrasound examination helps to identify and evaluate them well before birth.
Objectives: Present study was undertaken to evaluate the incidence of central nervous system anomalies in utero by ultrasound and to confirm them by autopsy or postnatal examination.
Method: Ultrasound screening of 7485 pregnant women was performed. Pregnancy with ultrasound findings of central nervous system anomalies were followed up. Prenatal ultrasound findings were confirmed by autopsy in cases of therapeutic abortions and fetal losses. In case of live birth postnatal findings were noted.
Results: Ultrasound detected central nervous system malformations in 24 fetuses. Ultrasound findings were matching in 83% on autopsy. Autopsy and postnatal findings together were matching with ultrasound in 85.7%. Two cases had additional minor findings on autopsy.
Conclusion: The incidence of central nervous system malformations on ultrasound was 0.31%. Autopsy and postnatal examination showed high degree of correlation with ultrasound findings.
[
FULL TEXT ] | [ PDF]